| Place of Origin: | CHINA |
|---|---|
| Brand Name: | Allbiosyn |
| CAS No.: | 110764-79-9 | Molecular Formula: | C40H49N4O9P |
|---|---|---|---|
| Molecular Weight: | 760.82 | Appearance: | White Powder |
| Purity: | HPLC ≥99.0% | Storage: | -20℃ |
5'-O-DMTr-2'-O-methyluridine 3'-CE phosphoramidite is a modified, phosphoramidite nucleoside. It is used in the synthesis of DNA and RNA. 5'-O-DMTr-2'-O-methyluridine 3'-CE phosphoramidite is an antiviral agent that inhibits viral replication by inhibiting viral protein synthesis. It has been shown to be active against HIV, Hepatitis B virus, and Hepatitis C virus. The compound also has anticancer properties and has been shown to inhibit tumor growth in animal models. 5'-O-DMTr-2'-O-methyluridine 3'-CE phosphoramidite is a novel synthetic nucleoside that can be used as an alternative to deoxyribonucleosides in the synthesis of DNA and RNA.
A phosphoramidite (RO)2PNR2 is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR2 moiety.
