| Place of Origin: | CHINA |
|---|---|
| Brand Name: | Allbiosyn |
| CAS No.: | 110782-31-5 | Molecular Formula: | C48H54N7O8P |
|---|---|---|---|
| Molecular Weight: | 887.96 | Appearance: | White Powder |
| Purity: | HPLC ≥99.0% | Storage: | -20℃ |
N6-Benzoyl-5'-O-DMTr-2'-O-methyladenosine 3'-CE phosphoramidite is a nucleoside phosphoramidite used as a building block in the chemical synthesis of oligonucleotides containing a 2’-O-methyl adenosine nucleoside unit. The use of a chemical synthesis rather than an enzymatic one allows oligonucleotides of a desired sequence to be produced. 3’-Cyanoethyl phosphoramidites are typically used by substitution of the di-isopropylamine group with an appropriate alcohol in the presence of an azole catalyst. Oligonucleotides containing 2'-O-methylribonucleoside units have shown site-specific cleavage with E. coli RNase H, either at a hairpin loop or at a stem region.
