CAS No.: | 150780-67-9 | Molecular Formula: | C45H56N7O9P |
---|---|---|---|
Molecular Weight: | 869.94 | Appearance: | White Powder |
Purity: | HPLC ≥99.0% | Storage: | -20℃ |
5'-O-DMTr-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite is a labile, thermally sensitive chemical compound. It is used as a building block for the synthesis of oligonucleotides.
A phosphoramidite (RO)2PNR2 is a monoamide of a phosphite diester. The key feature of phosphoramidites is their markedly high reactivity towards nucleophiles catalyzed by weak acids e.c., triethylammonium chloride or 1H-tetrazole. In these reactions, the incoming nucleophile replaces the NR2 moiety.