| Place of Origin: | China |
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| Price: | Negotiable |
| Packaging Details: | 20g, 100g, 500g,1kg |
| Delivery Time: | 7-15 workdays |
| Payment Terms: | LC, T/T, PayPal, Western Union, Small-amount payment, Money Gram |
| Supply Ability: | 10kg/month |
| Highlight: | NHMMTr-C8 Phosphoramidite,Colorless NHMMTr-C8 Phosphoramidite,NHMMTr-C8 Phosphoramidite oil |
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Colorless to light yellow oil, free from visible foreign matter, UPLC≥97.0%
Product Name: NHMMTr-C8 Phosphoramidite
Product Description:
NHMMTr-C8 Phosphoramidite is a high-quality building block used in the synthesis of oligonucleotides for various molecular biology and biotechnology applications. It belongs to the class of phosphoramidites and is specifically designed for solid-phase DNA synthesis. NHMMTr-C8 Phosphoramidite offers excellent efficiency, stability, and compatibility, making it an ideal choice for the production of high-quality oligonucleotides.
Key Features:
Phosphoramidite Building Block: NHMMTr-C8 Phosphoramidite serves as a key building block for the synthesis of oligonucleotides. It contains a phosphoramidite group that enables efficient coupling reactions with other nucleotides during solid-phase DNA synthesis.
N-Methylmorpholine (NMM) Trityl Protecting Group: The NHMMTr-C8 phosphoramidite is protected with an N-methylmorpholine (NMM) trityl group, providing excellent stability and protection during the synthesis process. This protecting group ensures high coupling efficiency and minimizes the formation of truncation products.
C8 Spacer: The presence of a C8 spacer in NHMMTr-C8 Phosphoramidite provides increased hydrophobicity and rigidity, which aids in the purification and isolation of synthesized oligonucleotides. The spacer also enhances the stability and compatibility of the oligonucleotides in downstream applications.
High Purity and Quality: NHMMTr-C8 Phosphoramidite is manufactured under stringent quality control standards to ensure high purity and consistency. It meets the requirements for reliable and reproducible synthesis of oligonucleotides.
Parameters:
Functions:
Oligonucleotide Synthesis: NHMMTr-C8 Phosphoramidite is an essential component in the solid-phase DNA synthesis process, enabling the stepwise assembly of oligonucleotides with high efficiency and purity.
Coupling Efficiency: The NMM trityl protecting group on NHMMTr-C8 Phosphoramidite ensures high coupling efficiency during oligonucleotide synthesis, minimizing the formation of deletion or insertion errors.
Stability and Compatibility: The C8 spacer in NHMMTr-C8 Phosphoramidite enhances the stability and compatibility of synthesized oligonucleotides, making them suitable for various downstream applications, such as PCR, sequencing, gene synthesis, and molecular diagnostics.
Purification and Isolation: The C8 spacer also aids in the purification and isolation of oligonucleotides, facilitating the removal of impurities and truncated sequences during the synthesis process.
