CAS No.: | 40615-39-2 | Molecular Weight: | 544.60 |
---|---|---|---|
Molecular Formula: | C31H32N2O7 | Storage: | 2-8℃,in Tightly Closed Container,protected From Light And Humidity. |
Purity: | HPLC ≥99.0% |
5’-O-DMTr-thymidine is also known as 5’-O-(4,4’-dimethoxytrityl)thymidine. It is a key deoxynucleoside building block that is protected with a dimethoxytrityl group in the 5-O-position of the deoxy-ribose moiety, leaving the 3-hydroxyl free for modification. It is used a convenient starting point for nucleotide synthesis. 5’-O-DMTr-thymidine can be converted into 3’-O-phosphoramidite derivatives for oligonucleotide synthesis. Additionally, 5’-O-DMTr-thymidine can be converted into more stable 1-N-protected derivatives.