CAS No.: | 81279-39-2 | Molecular Weight: | 769.97 |
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Molecular Formula: | C41H51N5O8Si | Storage: | 2-8℃,in Tightly Closed Container,protected From Light And Humidity. |
Purity: | HPLC ≥99.0% | ||
Highlight: | 5'-O-DMTr-2'-O-TBDMS-rG(iBu) |
2'-O-(tert-Butyldimethylsilyl)-5'-O-DMTr-N2-isobutyryl-guanosine is a synthetic nucleoside that has been modified with a tert-butyldimethylsilyl group. This modification is used to improve the efficiency of coupling reactions between nucleosides and phosphoramidites in oligonucleotide synthesis. The 2'-O-(tert-Butyldimethylsilyl)-5'-O-DMTr-N2-isobutyryl guanosine is also used as a chromophore in spectroscopy experiments and as a ligand in metal coordination chemistry.