DMTr-2'-OMe-5-Me-Ur

White, off-white to faint yellow powder ,2-8℃, Keep in a dark and dry place, HPLC ≥99%

Product Name: DMTr-2'-OMe-5-Me-Ur

Product Description:

DMTr-2'-OMe-5-Me-Ur is a modified nucleoside designed for nucleic acid research, therapeutic development, and related applications. It possesses unique structural features and enhanced properties that offer various advantages in terms of stability, functionality, and applications. The following features, parameters, and functions highlight the key aspects of this product:

1. Chemical Structure: DMTr-2'-OMe-5-Me-Ur is a modified uridine nucleoside with a dimethoxytrityl (DMTr) group protecting the 5'-hydroxyl group, a methoxyl group at the 2'-position, and a methyl group at the 5-position of the uracil ring. This modification introduces specific properties while retaining the natural structure of uridine.

2. Molecular Formula: C26H31N2O7

3. Molecular Weight: 477.54 g/mol

4. Physical Properties: Off-white to pale yellow powder

5. Solubility: Soluble in common organic solvents

Key Features and Functions:

1. Protection of 5'-Hydroxyl Group: The DMTr group in DMTr-2'-OMe-5-Me-Ur protects the 5'-hydroxyl group, allowing for controlled deprotection during oligonucleotide synthesis.

2. Nucleic Acid Research: DMTr-2'-OMe-5-Me-Ur serves as a valuable tool in nucleic acid research, including RNA synthesis, RNA modification studies, and RNA-protein interaction investigations.

3. Chemical Synthesis: It can be used as a building block in chemical synthesis for the preparation of modified RNA molecules, RNA probes, or other RNA-based materials.

4. Therapeutic Development: The unique structural features of DMTr-2'-OMe-5-Me-Ur make it a promising candidate for therapeutic development, particularly in the field of RNA-based therapeutics and gene regulation.

5. Stability in Biological Systems: The modifications in DMTr-2'-OMe-5-Me-Ur enhance its stability in biological systems, allowing for improved cellular uptake and potential applications in RNA drug delivery systems.

Table: Properties of DMTr-2'-OMe-5-Me-Ur

In summary, DMTr-2'-OMe-5-Me-Ur is a modified nucleoside designed for nucleic acid research, therapeutic development, and chemical synthesis applications. It offers protection of the 5'-hydroxyl group, making it suitable for controlled deprotection in oligonucleotide synthesis. Its unique structural features make it valuable in RNA research, chemical synthesis, and potential therapeutic development in the field of RNA-based therapeutics and gene regulation.