N4-Ac-2'-F-dC

White powder, 2-8℃, Keep in a dark and dry place ,HPLC ≥99%

Product Name: N4-Ac-2'-F-dC

Product Description:

N4-Ac-2'-F-dC is a modified nucleoside designed for nucleic acid research, therapeutic development, and related applications. It possesses unique structural features and enhanced properties that offer various advantages in terms of stability, functionality, and applications. The following features, parameters, and functions highlight the key aspects of this product:

1. Chemical Structure: N4-Ac-2'-F-dC is a modified cytidine nucleoside with an acetyl group attached to the N4-position and a fluorine atom attached to the 2'-position of the ribose sugar. This modification introduces specific properties while retaining the natural structure of cytidine.

2. Molecular Formula: C12H14FN3O6

3. Molecular Weight: 329.25 g/mol

4. Physical Properties: Off-white to pale yellow powder

5. Solubility: Soluble in water and common organic solvents

Key Features and Functions:

1. Enhanced Stability: The N4-acetyl (N4-Ac) modification in N4-Ac-2'-F-dC enhances its stability, making it suitable for various applications requiring resistance to enzymatic degradation.

2. Nucleic Acid Research: N4-Ac-2'-F-dC serves as a valuable tool in nucleic acid research, including DNA synthesis, DNA sequencing, and investigations of DNA-protein interactions.

3. Antisense Oligonucleotides: The N4-Ac modification in N4-Ac-2'-F-dC improves the binding affinity of oligonucleotides to complementary RNA targets, making it effective for antisense therapy and gene expression modulation.

4. Chemical Synthesis: It can be used as a building block in chemical synthesis for the preparation of modified nucleic acids, nucleic acid probes, or other nucleic acid-based materials.

5. Therapeutic Development: The unique structural features of N4-Ac-2'-F-dC make it a promising candidate for therapeutic development, particularly in the field of antisense oligonucleotides or RNA-based therapeutics.

Properties of N4-Ac-2'-F-dC

In summary, N4-Ac-2'-F-dC is a modified nucleoside designed for nucleic acid research, therapeutic development, and chemical synthesis applications. It offers enhanced stability and serves as a versatile tool in nucleic acid studies. Its unique structural features make it suitable for applications in DNA research, antisense therapy, and therapeutic development using RNA-based approaches.