N2-iBu-2'-dG

White to off-white powder, 2-8℃, Keep in a dark and dry place, 

HPLC ≥98%

Product Name: N2-iBu-2'-dG

Product Description:

N2-iBu-2'-dG is a modified nucleoside designed for nucleic acid research, therapeutic development, and related applications. It possesses unique structural features and enhanced properties that offer various advantages in terms of stability, functionality, and applications. The following features, parameters, and functions highlight the key aspects of this product:

1. Chemical Structure: N2-iBu-2'-dG is a modified guanosine nucleoside with an isobutyl group attached to the N2-position and a modified ribose sugar at the 2'-position. This modification introduces specific properties while retaining the natural structure of guanosine.

2. Molecular Formula: C15H23N5O5

3. Molecular Weight: 369.37 g/mol

4. Physical Properties: Off-white to pale yellow powder

5. Solubility: Soluble in water and common organic solvents

Key Features and Functions:

1. Enhanced Stability: The N2-isobutyl (N2-iBu) modification in N2-iBu-2'-dG enhances its stability, making it suitable for various applications requiring resistance to enzymatic degradation.

2. Nucleic Acid Research: N2-iBu-2'-dG serves as a valuable tool in nucleic acid research, including DNA synthesis, DNA sequencing, and investigations of DNA-protein interactions.

3. Chemical Synthesis: It can be used as a building block in chemical synthesis for the preparation of modified nucleic acids, nucleic acid probes, or other nucleic acid-based materials.

4. Therapeutic Development: The unique structural features of N2-iBu-2'-dG make it a promising candidate for therapeutic development, particularly in the field of gene regulation and nucleic acid-based therapies.

5. Stability in Biological Systems: The N2-isobutyl modification enhances the stability of N2-iBu-2'-dG in biological systems, allowing for improved cellular uptake and potential applications in drug delivery systems.

Properties of N2-iBu-2'-dG

In summary, N2-iBu-2'-dG is a modified nucleoside designed for nucleic acid research, therapeutic development, and chemical synthesis applications. It offers enhanced stability and serves as a versatile tool in nucleic acid studies. Its unique structural features make it suitable for applications in DNA research, chemical synthesis, and potential therapeutic development in the field of gene regulation and nucleic acid-based therapies.