| Place of Origin: | China |
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| Price: | Negotiable |
| Packaging Details: | 20g, 100g, 500g,1kg |
| Delivery Time: | 7-15 workdays |
| Payment Terms: | LC, T/T, PayPal, Western Union, Small-amount payment, Money Gram |
| Supply Ability: | 100kg/month |
| CAS NO.: | 2140-71-8 | ||
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| Highlight: | 2'-O-Me Nucleosides,2'-OMe-Gr,2'-OMe-Gr Nucleoside |
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White to off-white powder, 2-8℃ (for long-term), HPLC ≥99%
Product Name: 2'-OMe-Gr
Product Description:
2'-OMe-Gr is a modified nucleoside designed for nucleic acid research, therapeutic development, and related applications. It possesses unique structural features and enhanced properties that offer various advantages in terms of stability, functionality, and applications. The following features, parameters, and functions highlight the key aspects of this product:
Chemical Structure: 2'-OMe-Gr is a modified guanosine nucleoside with a 2'-O-methyl (2'-OMe) modification on the ribose sugar. This modification introduces specific properties while retaining the natural structure of guanosine.
Molecular Formula: C11H15N5O5
Molecular Weight: 297.27 g/mol
Physical Properties: Off-white to pale yellow powder
Solubility: Soluble in water and common organic solvents
Key Features and Functions:
Enhanced Stability: The 2'-O-methyl modification in 2'-OMe-Gr enhances its stability, making it suitable for various applications requiring resistance to enzymatic degradation.
Nucleic Acid Research: 2'-OMe-Gr serves as a valuable tool in nucleic acid research, including RNA synthesis, RNA structure determination, and investigations of RNA-protein interactions.
RNA Therapeutics: The 2'-O-methyl modification in 2'-OMe-Gr provides improved resistance to nuclease degradation and enhances the pharmacokinetic properties of RNA-based therapeutics.
RNA Interference (RNAi): 2'-OMe-Gr can be incorporated into small interfering RNA (siRNA) molecules for gene silencing applications, enabling targeted and specific knockdown of gene expression.
Chemical Synthesis: It can be used as a building block in chemical synthesis for the preparation of modified nucleic acids, nucleic acid probes, or other nucleic acid-based materials.
Properties of 2'-OMe-Gr
| Property | Description |
|---|---|
| Chemical Formula | C11H15N5O5 |
| Molecular Weight | 297.27 g/mol |
| Physical Appearance | Off-white to pale yellow powder |
| Solubility | Soluble in water and common organic solvents |
| Key Features | - Enhanced stability |
| - Versatile nucleic acid research tool | |
| - Applications in RNA therapeutics and RNAi | |
| - Chemical synthesis applications |
In summary, 2'-OMe-Gr is a modified nucleoside designed for nucleic acid research, therapeutic development, and chemical synthesis applications. It offers enhanced stability and serves as a versatile tool in nucleic acid studies. Its unique structural features make it suitable for applications in RNA research, therapeutic development, and gene silencing through RNA interference (RNAi).
