DMTr-2'-O-TBDMS-Ur-3'-succinate, TEA salt

Basic Information
Place of Origin: China
Price: Negotiable
Packaging Details: 10g, 100g, 1000g, 5kg , 25kg
Delivery Time: 7-15 workdays
Payment Terms: LC, T/T, PayPal, Western Union, Small-amount payment, Money Gram
Supply Ability: 5000kg/Month
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DMT-2'-O-TBDMS-Ur-3'-succinate

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RNA (2'-O-TBDMS) Succinates

White to yellow powder, -20℃,in tightly closed containers,protected from humidity,HPLC ≥98%

 

 

Product Name: DMTr-2'-O-TBDMS-Ur-3'-succinate, TEA salt

 

Product Description:

 

DMTr-2'-O-TBDMS-Ur-3'-succinate, TEA salt is a high-quality nucleotide phosphoramidite used in oligonucleotide synthesis and molecular biology research. It incorporates a modified uridine nucleotide analog with a succinate linker, a 2'-O-TBDMS (tert-butyldimethylsilyl) protecting group, and a 3'-O-dimethoxytrityl (DMTr) protecting group. The TEA (Triethylammonium) salt form enhances solubility and facilitates efficient synthesis. This phosphoramidite offers improved stability and controlled incorporation during oligonucleotide synthesis. DMTr-2'-O-TBDMS-Ur-3'-succinate, TEA salt is compatible with standard synthesis protocols and can be used with automated DNA synthesizers. It provides researchers with a valuable tool for the synthesis of modified DNA oligonucleotides for various applications in molecular biology research.

 

 

Parameter Table:

 

Parameter Description
Composition Nucleotide phosphoramidite with modified uridine nucleotide analog, succinate linker, 2'-O-TBDMS protecting group, and 3'-O-dimethoxytrityl (DMTr) protecting group
Purity High purity
Solubility Soluble in typical organic solvents
Stability Enhanced stability during synthesis and storage
Compatibility Compatible with standard oligonucleotide synthesis protocols and automated DNA synthesizers
Applications 1. Site-specific incorporation of modified uridine analogs
  2. RNA labeling and detection using fluorescent or other reporter molecules
  3. Development of modified DNA oligonucleotides for hybridization-based assays
  4. Nucleotide modifications for improved RNA stability and resistance

Contact Details
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