7-I-7-deaza-dG 7-deaza-7-Iodo-2'-deoxyguanosine

Product Name: 7-I-7-deaza-dG

Product Description:

7-I-7-deaza-dG is a modified nucleoside designed for nucleic acid research, therapeutic development, and related applications. It possesses unique structural features and enhanced properties that offer various advantages in terms of stability, functionality, and applications. The following features, parameters, and functions highlight the key aspects of this product:

1. Chemical Structure: 7-I-7-deaza-dG is a modified deoxyguanosine nucleoside with a 7-iodo substitution and a 7-deaza modification. This modification replaces the nitrogen at the 7-position of the guanine base with a carbon atom, resulting in a modified nucleoside with distinct properties.

2. Molecular Formula: C11H12IN5O4

3. Molecular Weight: 403.14 g/mol

4. Physical Properties: Off-white to pale yellow powder

5. Solubility: Soluble in water and common organic solvents

Key Features and Functions:

1. Enhanced Stability: The 7-I-7-deaza modification enhances the stability of the nucleoside, making it suitable for various applications requiring resistance to enzymatic degradation.

2. Nucleic Acid Research: 7-I-7-deaza-dG serves as a valuable tool in nucleic acid research, including DNA synthesis, DNA sequencing, and investigations of DNA-protein interactions.

3. Nucleic Acid Labeling: The 7-iodo substitution in 7-I-7-deaza-dG provides a unique handle for labeling and detection purposes, allowing researchers to track and visualize DNA molecules.

4. Structural Studies: The 7-deaza modification in 7-I-7-deaza-dG reduces the potential for non-specific hydrogen bonding, making it particularly useful for studying DNA structure, stability, and folding.

5. Therapeutic Development: The unique structural features of 7-I-7-deaza-dG make it a promising candidate for therapeutic development, especially in the field of antisense oligonucleotides or DNA-based therapeutics.

Table: Properties of 7-I-7-deaza-dG

In summary, 7-I-7-deaza-dG is a modified nucleoside designed for nucleic acid research, therapeutic development, and various applications. It offers enhanced stability and serves as a versatile tool in nucleic acid studies, including DNA research, labeling, and structural investigations. Its unique structural features make it a promising candidate for therapeutic development in the field of DNA-based therapeutics.